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DNA Probes Summary

Description: Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.

Also Known As: Conserved Gene Probes; DNA Hybridization Probes; Whole Chromosomal Probes; Whole Genomic DNA Probes; Chromosomal Probes, Whole Show All >>

Networked: 1031 relevant articles (6 outcomes, 102 trials/studies) for this Bio-Agent

Key Diseases for which DNA Probes is Relevant

  1. Infection : 2 outcomes 5 studies in 73 results
  2. Neoplasms (Cancer) : 1 outcome 9 studies in 131 results
  3. Down Syndrome (Down's Syndrome) : 1 outcome 2 studies in 11 results
  4. Communicable Diseases (Infectious Diseases) : 1 outcome in 13 results
  5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia) : 1 outcome in 5 results
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Drugs Related to DNA Probes

  1. Monoclonal Antibodies
  2. Radioisotopes (Radionuclides)
  3. trisomy Chromosome 8
  4. DNA (Deoxyribonucleic Acid)
  5. Paraffin
  6. Genetic Markers (Genetic Marker)
  7. Factor VIII (Coagulation Factor VIII)
  8. Fluorescent Dyes (Fluorescent Probes)
  9. Formaldehyde (Formol)
  10. Biotin (Vitamin H)
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Therapies Related to DNA Probes

  1. Transplants (Transplant)
  2. Drug Therapy (Chemotherapy)
  3. Electrodes (Electrode)
  4. Examination Tables
  5. Laser Therapy (Surgery, Laser)
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