Search Login Register

Wegener Granulomatosis (Wegener's Granulomatosis) Summary

Description: A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and kidneys. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against neutrophil proteinase-3 (WEGENER AUTOANTIGEN).

Also Known As: Wegener's Granulomatosis; Granulomatosis, Wegener; Granulomatosis, Wegener's

Networked: 1990 relevant articles (134 outcomes, 128 trials/studies) for this Disease

Key Drugs and Agents for Wegener Granulomatosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclophosphamide (Cytoxan) : 43 outcomes 20 studies in 237 results : FDA 10 Generic
  2. Antineutrophil Cytoplasmic Antibodies (ANCA) : 19 outcomes 35 studies in 733 results : IBA
  3. rituximab (Mabthera) : 18 outcomes 6 studies in 69 results : FDA 3
  4. Methotrexate (Mexate) : 14 outcomes 7 studies in 38 results : FDA 8 Generic
  5. Prednisolone (Predate) : 11 outcomes 2 studies in 28 results : FDA 55 Generic
  6. Adrenal Cortex Hormones (Corticosteroids) : 10 outcomes 5 studies in 54 results : IBA
  7. Prednisone (Sone) : 10 outcomes 3 studies in 35 results : FDA 119 Generic
  8. Glucocorticoids : 10 outcomes 2 studies in 22 results : IBA
  9. Azathioprine (Imuran) : 7 outcomes 2 studies in 29 results : FDA 7 Generic
  10. TNFR-Fc fusion protein (etanercept) : 6 outcomes 22 studies in 29 results : FDA 2
Show All >>

Diseases Related to Wegener Granulomatosis

  1. Vasculitis (Vasculitides)
  2. Microscopic Polyangiitis
  3. Sarcoidosis (Schaumann Disease)
  4. Glomerulonephritis
  5. Systemic Vasculitis
Show All >>

Key Therapies for Wegener Granulomatosis

Efficacy Chart >>
  1. Remission Induction : 4 outcomes 3 studies in 17 results
  2. Aftercare (After-Treatment) : 3 outcomes 2 studies in 13 results
  3. Plasmapheresis : 3 outcomes 1 study in 11 results
  4. Plasma Exchange : 2 outcomes in 15 results
  5. Transplants (Transplant) : 1 outcome in 22 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.