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Urokinase-Type Plasminogen Activator (Urokinase) Summary

Description: A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.

Also Known As: Urokinase; Urokinase Type Plasminogen Activator; U-PA; U-Plasminogen Activator; Abbokinase Show All >>

Networked: 5186 relevant articles (240 outcomes, 576 trials/studies) for this Drug

Key Diseases for which Urokinase-Type Plasminogen Activator is Relevant

  1. Thrombosis (Thrombus) : 55 outcomes 26 studies in 507 results
  2. Myocardial Infarction : 18 outcomes 32 studies in 213 results
  3. Stroke (Strokes) : 18 outcomes 16 studies in 109 results
  4. Neoplasms (Cancer) : 17 outcomes 83 studies in 1301 results
  5. Venous Thrombosis (Deep-Vein Thrombosis) : 13 outcomes 10 studies in 109 results
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Drugs Related to Urokinase-Type Plasminogen Activator

  1. Tissue Plasminogen Activator (Alteplase)
  2. Plasminogen Activators (Plasminogen Activator)
  3. Streptokinase
  4. Heparin (Liquaemin)
  5. Plasminogen
  6. Anti-Bacterial Agents (Antibiotics)
  7. Plasminogen Activator Inhibitor 1
  8. Fibrinolytic Agents (Antithrombotic Agents)
  9. Batroxobin
  10. Fibrin
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Therapies Related to Urokinase-Type Plasminogen Activator

  1. Catheters
  2. Thrombolytic Therapy
  3. Angioplasty (Angioplasty, Transluminal)
  4. Transplants (Transplant)
  5. Stents
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