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Genetic Translocation (Chromosomal Translocation) Summary

Description: A type of chromosome aberration characterized by CHROMOSOME BREAKAGE and transfer of the broken-off portion to another location, often to a different chromosome.

Also Known As: Chromosomal Translocation; Chromosomal Translocations; Translocation, Genetic; Genetic Translocations; Translocations, Chromosomal Show All >>

Networked: 1895 relevant articles (18 outcomes, 69 trials/studies) for this Disease

Key Drugs and Agents for Genetic Translocation

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. imatinib (Gleevec) : 3 outcomes in 7 results : FDA 3
  2. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor) : 2 outcomes in 7 results : IBA
  3. Paraffin : 1 outcome 5 studies in 24 results : IBA
  4. retinoic acid receptor alpha : 1 outcome 3 studies in 102 results : IBA
  5. T-Cell Antigen Receptors (T-Cell Receptor) : 1 outcome 2 studies in 40 results : IBA
  6. Etoposide (VP 16) : 1 outcome 1 study in 6 results : FDA 16 Generic
  7. Type II DNA Topoisomerases (Topoisomerase II) : 1 outcome in 15 results : IBA
  8. 1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB) : 1 outcome in 10 results : IBA
  9. Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta) : 1 outcome in 7 results : IBA
  10. Oxidoreductases : 1 outcome in 6 results : IBA
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Diseases Related to Genetic Translocation

  1. Neoplasms (Cancer)
  2. Sarcoma (Soft Tissue Sarcoma)
  3. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
  4. Genomic Instability
  5. Myeloproliferative Disorders (Myeloproliferative Disorder)
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Key Therapies for Genetic Translocation

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 2 outcomes 1 study in 19 results
  2. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 1 outcome in 3 results
  3. Therapeutics : 5 results
  4. Radiotherapy : 3 results
  5. Transplants (Transplant) : 2 results
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