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Thoracic Outlet Syndrome (Syndrome, Thoracic Outlet) Summary

Description: A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a CERVICAL RIB, anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).

Also Known As: Syndrome, Thoracic Outlet; Aperture Syndrome, Thoracic Outlet; Arterial Thoracic Outlet Syndrome; Nerve Compression Syndrome, Thoracic Outlet; Neurogenic Thoracic Outlet Syndrome Show All >>

Networked: 139 relevant articles (8 outcomes, 12 trials/studies) for this Disease

Key Drugs and Agents for Thoracic Outlet Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Botulinum Toxins (Botulinum Toxin) : 1 study in 5 results : IBA
  2. Type A Botulinum Toxins (Botulinum A Toxin) : 1 study in 2 results : FDA 2
  3. tebufenozide (Mimic) : 1 study in 2 results : IBA
  4. Seprafilm : 1 study in 1 result : IBA
  5. Aberrant subclavian artery : 5 results : IBA
  6. glucuronyl glucosamine glycan sulfate (Vessel) : 3 results : IBA
  7. Carbon Monoxide : 2 results : IBA
  8. tranilast (N 5') : 2 results : IBA
  9. Urokinase-Type Plasminogen Activator (Urokinase) : 1 result : FDA 2
  10. Titanium : 1 result : IBA
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Diseases Related to Thoracic Outlet Syndrome

  1. Thrombosis (Thrombus)
  2. Cicatrix (Scar)
  3. Pain (Aches)
  4. Radiculopathy (Radiculopathy, Cervical)
  5. Paralysis (Palsy)
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Key Therapies for Thoracic Outlet Syndrome

Efficacy Chart >>
  1. Decompression : 2 outcomes 4 studies in 21 results
  2. Surgical Decompression : 2 outcomes 1 study in 16 results
  3. Injections : 1 outcome 1 study in 3 results
  4. Aftercare (After-Treatment) : 1 outcome 1 study in 1 result
  5. Thrombolytic Therapy : 1 outcome in 4 results
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