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Giant Cell Arteritis (Horton Disease) Summary

Description: A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)

Also Known As: Horton Disease; Juvenile Temporal Arteritis; Arteritis, Temporal; Cranial Arteritis; Arteritis, Giant Cell, Horton Show All >>

Networked: 1117 relevant articles (43 outcomes, 77 trials/studies) for this Disease

Key Drugs and Agents for Giant Cell Arteritis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Adrenal Cortex Hormones (Corticosteroids) : 12 outcomes 4 studies in 109 results : IBA
  2. Prednisone (Sone) : 9 outcomes 2 studies in 49 results : FDA 119 Generic
  3. tocilizumab : 6 outcomes 6 studies in 16 results : FDA 2
  4. Steroids : 3 outcomes 1 study in 52 results : IBA
  5. glucuronyl glucosamine glycan sulfate (Vessel) : 2 outcomes 4 studies in 172 results : IBA
  6. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor) : 2 outcomes 3 studies in 15 results : IBA
  7. Glucocorticoids : 2 outcomes 1 study in 23 results : IBA
  8. infliximab (Remicade) : 2 outcomes 1 study in 11 results : FDA 2
  9. C-Reactive Protein : 1 outcome 4 studies in 31 results : IBA
  10. Methotrexate (Mexate) : 1 outcome 4 studies in 21 results : FDA 8 Generic
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Diseases Related to Giant Cell Arteritis

  1. Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis)
  2. Takayasu Arteritis (Arteritis, Takayasu's)
  3. Giant Cell Arteritis (Horton Disease)
  4. Vasculitis (Vasculitides)
  5. Aortitis
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Key Therapies for Giant Cell Arteritis

Efficacy Chart >>
  1. Cardiopulmonary Resuscitation (CPR) : 1 outcome 1 study in 1 result
  2. Aftercare (After-Treatment) : 1 outcome in 10 results
  3. Injections : 1 outcome in 2 results
  4. Oral Administration : 1 study in 1 result
  5. Hysterectomy : 6 results
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