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Suramin (Suramin Sodium) Summary

Description: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.

Also Known As: Suramin Sodium; Germanin; Moranil; Naganin; Naganol Show All >>

Networked: 749 relevant articles (55 outcomes, 162 trials/studies) for this Bio-Agent

Key Diseases for which Suramin is Relevant

  1. Infection : 8 outcomes 4 studies in 66 results
  2. Neoplasms (Cancer) : 6 outcomes 41 studies in 202 results
  3. Trypanosomiasis : 4 outcomes 4 studies in 42 results
  4. Fibrosis (Cirrhosis) : 4 outcomes 2 studies in 19 results
  5. Prostatic Neoplasms (Prostate Cancer) : 3 outcomes 26 studies in 85 results
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Drugs Related to Suramin

  1. Hormones
  2. Melarsoprol (Mel B)
  3. Paclitaxel (Taxol)
  4. Intercellular Signaling Peptides and Proteins (Growth Factors)
  5. Hydrocortisone (Cortisol)
  6. Eflornithine (Ornidyl)
  7. Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)
  8. Cisplatin (Platino)
  9. Heparin (Liquaemin)
  10. O-(chloroacetylcarbamoyl)fumagillol (TNP 470)
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Therapies Related to Suramin

  1. Transplants (Transplant)
  2. Drug Therapy (Chemotherapy)
  3. Heterologous Transplantation (Xenotransplantation)
  4. Spinal Injections
  5. Nephrectomy
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