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Shy-Drager Syndrome
Summary
Description:
A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536)
Also Known As:
Dysautonomia-Orthostatic Hypotension Syndrome; Syndrome, Dysautonomia-Orthostatic Hypotension; Autonomic Failures, Progressive; Dysautonomia Orthostatic Hypotension Syndrome; Dysautonomia-Orthostatic Hypotension Syndromes Show All >>
Networked: 142
relevant articles (3 outcomes,
6 trials/studies)
for this Disease
Key Drugs and Agents for Shy-Drager Syndrome
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
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Idiopathic orthostatic hypotension
:
1 outcome 1 study in 21 results
: IBA
-
Propranolol (Inderal)
:
1 outcome in 3 results
:
FDA 158
Generic
-
Midodrine (Midon)
:
1 outcome in 3 results
:
FDA 7
Generic
-
Trimethaphan (Trimetaphan)
:
1 outcome in 1 result
: IBA
-
Norepinephrine (Noradrenaline)
:
1 study in 16 results
:
FDA 5
Generic
-
Dopamine (Intropin)
:
1 study in 5 results
:
FDA 36
Generic
-
SAS
:
1 study in 2 results
: IBA
-
Dopamine Agonists (Dopamine Agonist)
:
1 study in 1 result
: IBA
-
Xenon
:
1 study in 1 result
: IBA
-
GABA-A Receptors (GABA(A) Receptor)
:
1 study in 1 result
: IBA
Show All >>
Diseases Related to Shy-Drager Syndrome
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Orthostatic Hypotension (Postural Hypotension)
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Multiple System Atrophy
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Parkinson Disease (Parkinson's Disease)
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Pure Autonomic Failure
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Hypertension (High Blood Pressure)
Show All >>
Key Therapies for Shy-Drager Syndrome
Efficacy Chart >>
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Intravenous Infusions
:
1 study in 3 results
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Denervation
:
3 results
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General Anesthesia
:
3 results
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Anesthesia
:
3 results
-
Sympathectomy (Sympathectomies)
:
2 results
Show All >>
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