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Retinaldehyde
(Retinal)
Summary
Description:
A carotenoid constituent of visual pigments. It is the oxidized form of retinol which functions as the active component of the visual cycle. It is bound to the protein opsin forming the complex rhodopsin. When stimulated by visible light, the retinal component of the rhodopsin complex undergoes isomerization at the 11-position of the double bond to the cis-form; this is reversed in "dark" reactions to return to the native trans-configuration.
Also Known As:
Retinal; Retinene; Vitamin A Aldehyde; 11-cis-Retinal; 11 cis Retinal Show All >>
Networked: 27699
relevant articles (794 outcomes,
2708 trials/studies)
for this Bio-Agent
Key Diseases for which Retinaldehyde is
Relevant
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Ischemia
:
74 outcomes 188 studies in 1462 results
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Diabetic Retinopathy (Retinopathy, Diabetic)
:
58 outcomes 353 studies in 2013 results
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Macular Degeneration (Age-Related Maculopathy)
:
49 outcomes 127 studies in 1379 results
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Macular Edema
:
44 outcomes 62 studies in 769 results
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Glaucoma
:
34 outcomes 145 studies in 1612 results
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Drugs Related to Retinaldehyde
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Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
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bevacizumab
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ROP
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Oxygen
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ranibizumab (Lucentis)
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Fluorescein (Funduscein)
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Triamcinolone Acetonide (Azmacort)
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Silicones
-
1-phenyl-3,3-dimethyltriazene (PDT)
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Vitamin E
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Therapies Related to Retinaldehyde
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Lasers (Laser)
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Light Coagulation
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Vitrectomy
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Intravitreal Injections
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Injections
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