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Pulmonary Alveolar Proteinosis Summary

Description: A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.

Also Known As: Alveolar Proteinoses, Pulmonary; Alveolar Proteinosis, Pulmonary; Proteinoses, Pulmonary Alveolar; Proteinosis, Pulmonary Alveolar; Pulmonary Alveolar Proteinoses

Networked: 439 relevant articles (24 outcomes, 17 trials/studies) for this Disease

Key Drugs and Agents for Pulmonary Alveolar Proteinosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) : 12 outcomes 4 studies in 136 results : IBA
  2. Acetaminophen (Paracetamol) : 3 outcomes 2 studies in 16 results : FDA 409 Generic
  3. rituximab (Mabthera) : 1 outcome 1 study in 4 results : FDA 3
  4. Autoantibodies : 1 outcome in 28 results : IBA
  5. Oxygen : 1 outcome in 9 results : IBA
  6. Nocardiosis : 1 outcome in 9 results : IBA
  7. Ambroxol (Mucosolvan) : 1 outcome in 3 results : IBA
  8. Carbon Monoxide : 1 outcome in 2 results : IBA
  9. Interleukin-17 (Interleukin 27) : 1 outcome in 1 result : IBA
  10. Immunosuppressive Agents (Immunosuppressants) : 1 outcome in 1 result : IBA
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Diseases Related to Pulmonary Alveolar Proteinosis

  1. Anoxia (Hypoxia)
  2. Lung Diseases (Lung Disease)
  3. Neoplasms (Cancer)
  4. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
  5. Interstitial Lung Diseases (Interstitial Lung Disease)
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Key Therapies for Pulmonary Alveolar Proteinosis

Efficacy Chart >>
  1. Respiratory Therapy (Therapy, Respiratory) : 2 outcomes in 4 results
  2. Drug Therapy (Chemotherapy) : 2 outcomes in 3 results
  3. General Anesthesia : 1 outcome in 5 results
  4. Plasmapheresis : 1 outcome in 2 results
  5. Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) : 1 outcome in 1 result
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