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Pregnanolone (Allopregnanolone) Summary

Description: A pregnane found in the urine of pregnant women and sows. It has anesthetic, hypnotic, and sedative properties.

Also Known As: Allopregnanolone; Eltanolone; 3 alpha, 5 beta-Tetrahydroprogesterone; 3 alpha-Hydroxy-5 alpha-pregnan-20-one; 3 alpha-Hydroxy-5 beta-pregnan-20-one; 3-Hydroxypregnan-20-one; 3beta-Hydroxy-5alpha-pregnan-20-one; Allopregnan-3 beta-ol-20-one; Epipregnanolone; Pregnan-3alpha-ol-20-one; Pregnanolone, (3alpha)-isomer; Pregnanolone, (3alpha, 5beta, 17-alpha)-isomer; Pregnanolone, (3alpha,5alpha)-isomer; Pregnanolone, (3alpha,5beta)-isomer; Pregnanolone, (3beta)-isomer; Pregnanolone, (3beta, 5alpha)-isomer; Pregnanolone, (3beta, 5alpha, 17alpha)-isomer; Pregnanolone, (3beta, 5alpha, 8alpha, 17beta)-isomer; Pregnanolone, (3beta, 5beta)-isomer; Pregnanolone, (3beta, 5beta, 17alpha)-isomer; Pregnanolone, (3beta, 5beta,14beta)-isomer; Pregnanolone, (5alpha)-isomer; 3 Hydroxypregnan 20 one; 3 alpha Hydroxy 5 alpha pregnan 20 one; 3 alpha Hydroxy 5 beta pregnan 20 one; 3 alpha, 5 beta Tetrahydroprogesterone; 3beta Hydroxy 5alpha pregnan 20 one; Allopregnan 3 beta ol 20 one; Pregnan 3alpha ol 20 one; alpha-Hydroxy-5 alpha-pregnan-20-one, 3; alpha-Hydroxy-5 beta-pregnan-20-one, 3; alpha-pregnan-20-one, 3 alpha-Hydroxy-5; beta-ol-20-one, Allopregnan-3; beta-pregnan-20-one, 3 alpha-Hydroxy-5; Pregnan-20-one, 3-hydroxy-, (3alpha,5beta)-

Networked: 313 relevant articles (21 outcomes, 54 trials/studies) for this Bio-Agent

Key Diseases for which Pregnanolone is Relevant

  1. Seizures (Seizure) : 7 outcomes 9 studies in 58 results
  2. Alzheimer Disease (Alzheimer's Disease) : 4 outcomes 5 studies in 20 results
  3. Weight Loss (Weight Reduction) : 2 outcomes in 2 results
  4. Diabetic Neuropathies (Diabetic Neuropathy) : 2 outcomes in 2 results
  5. Premenstrual Syndrome (Premenstrual Tension) : 1 outcome 5 studies in 18 results
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Drugs Related to Pregnanolone

  1. GABA-A Receptors (GABA(A) Receptor)
  2. gamma-Aminobutyric Acid (GABA)
  3. Progesterone
  4. Neurotransmitter Agents (Neurotransmitter)
  5. Steroids
  6. Ethanol (Ethyl Alcohol)
  7. Finasteride (Propecia)
  8. N-Methylaspartate (NMDA)
  9. Picrotoxin
  10. Pentylenetetrazole (Metrazol)
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Therapies Related to Pregnanolone

  1. Injections
  2. Therapeutics
  3. Analgesia
  4. Drug Therapy (Chemotherapy)
  5. Intraperitoneal Injections
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