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Poliomyelitis (Polio) Summary

Description: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)

Also Known As: Polio; Infantile Paralysis; Paralysis, Infantile; Polios; Encephalitis, Polio Show All >>

Networked: 4214 relevant articles (121 outcomes, 369 trials/studies) for this Disease

Key Drugs and Agents for Poliomyelitis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Vaccines : 42 outcomes 72 studies in 884 results : IBA
  2. alpha-Fetoproteins (AFP) : 12 outcomes 28 studies in 259 results : IBA
  3. Oral Poliovirus Vaccine (Sabin Vaccine) : 10 outcomes 10 studies in 225 results : IBA
  4. Inactivated Poliovirus Vaccine (Salk Vaccine) : 7 outcomes 5 studies in 138 results : FDA 1
  5. Antibodies : 6 outcomes 30 studies in 304 results : IBA
  6. Diphtheria-Tetanus-Pertussis Vaccine (DPT Vaccine) : 5 outcomes 6 studies in 67 results : IBA
  7. Poliovirus Vaccines : 5 outcomes 5 studies in 46 results : IBA
  8. Neutralizing Antibodies : 3 outcomes 17 studies in 167 results : IBA
  9. infanrix hexa : 3 outcomes in 8 results : IBA
  10. Antigens : 2 outcomes 26 studies in 202 results : IBA
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Diseases Related to Poliomyelitis

  1. Tetanus
  2. Diphtheria
  3. Whooping Cough (Pertussis)
  4. Measles
  5. Infection
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Key Therapies for Poliomyelitis

Efficacy Chart >>
  1. Injections : 2 outcomes 9 studies in 107 results
  2. Transplantation (Transplant Recipients) : 1 outcome 1 study in 38 results
  3. Arthroplasty : 1 outcome 1 study in 14 results
  4. Activities of Daily Living (ADL) : 1 outcome 1 study in 14 results
  5. Resistance Training : 1 outcome 1 study in 2 results
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