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Pimozide (Orap) Summary

Description: A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to HALOPERIDOL for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)

Also Known As: Orap; Antalon; ASTA Medica Brand of Pimozide; Janssen Brand of Pimozide; Orap forte Show All >>

Networked: 339 relevant articles (43 outcomes, 43 trials/studies) for this Drug

Key Diseases for which Pimozide is Relevant

  1. Tourette Syndrome (Tourette's Syndrome) : 9 outcomes 10 studies in 38 results
  2. Schizophrenia (Dementia Praecox) : 8 outcomes 7 studies in 42 results
  3. Tics (Tic) : 6 outcomes 4 studies in 23 results
  4. Paranoid Schizophrenia (Delusional Disorder) : 4 outcomes in 14 results
  5. Dystonia (Limb Dystonia) : 2 outcomes in 6 results
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Drugs Related to Pimozide

  1. Haloperidol (Haldol)
  2. Antipsychotic Agents (Antipsychotics)
  3. Risperidone (Risperdal Consta)
  4. Apomorphine
  5. Dopamine Receptors (Dopamine Receptor)
  6. Chlorpromazine (Thorazine)
  7. Sulpiride (neogama)
  8. Clozapine (Clozaril)
  9. Domperidone (Domperidon)
  10. Dopamine Antagonists
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Therapies Related to Pimozide

  1. Aftercare (After-Treatment)
  2. Injections
  3. Intraventricular Injections
  4. Intraperitoneal Injections
  5. Induced Hypothermia
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