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Pentoxifylline (Trental) Summary

Description: A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.

Also Known As: Trental; Oxpentifylline; Pentoxil; Agapurin; BL-191 Show All >>

Networked: 1978 relevant articles (286 outcomes, 482 trials/studies) for this Drug

Key Diseases for which Pentoxifylline is Relevant

  1. Intermittent Claudication : 19 outcomes 27 studies in 93 results
  2. Fibrosis (Cirrhosis) : 13 outcomes 21 studies in 74 results
  3. Alcoholic Hepatitis : 11 outcomes 13 studies in 55 results
  4. Sepsis (Septicemia) : 10 outcomes 14 studies in 81 results
  5. Reperfusion Injury : 9 outcomes 12 studies in 52 results
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Drugs Related to Pentoxifylline

  1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  2. Pentoxifylline (Trental)
  3. Adrenal Cortex Hormones (Corticosteroids)
  4. Vitamin E
  5. Prednisolone (Predate)
  6. Xanthine
  7. Aspirin (Acetylsalicylic Acid)
  8. Thalidomide (Thalomid)
  9. Nafronyl (Naftidrofuryl)
  10. cilostazol (Pletal)
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Therapies Related to Pentoxifylline

  1. Oral Administration
  2. Resuscitation
  3. Drug Therapy (Chemotherapy)
  4. Aftercare (After-Treatment)
  5. Intravenous Infusions
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