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Waldenstrom Macroglobulinemia (Macroglobulinemia) Summary

Description: A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity.

Also Known As: Macroglobulinemia; Waldenstrom's Macroglobulinemia; Familial Waldenstrom's Macroglobulinaemia; Lymphoma, Lymphocytic, Plasmacytoid; Primary Macroglobulinemia Show All >>

Networked: 1173 relevant articles (63 outcomes, 101 trials/studies) for this Disease

Key Drugs and Agents for Waldenstrom Macroglobulinemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. rituximab (Mabthera) : 17 outcomes 15 studies in 94 results : FDA 3
  2. fludarabine : 11 outcomes 8 studies in 51 results : IBA
  3. Cyclophosphamide (Cytoxan) : 6 outcomes 3 studies in 33 results : FDA 10 Generic
  4. Dexamethasone (Maxidex) : 5 outcomes 2 studies in 16 results : FDA 77 Generic
  5. Cladribine : 5 outcomes 1 study in 24 results : FDA 3 Generic
  6. bortezomib (Velcade) : 2 outcomes 11 studies in 32 results : FDA 1
  7. Chlorambucil (Leukeran) : 2 outcomes 2 studies in 21 results : FDA 1
  8. Prednisone (Sone) : 2 outcomes 1 study in 10 results : FDA 119 Generic
  9. Pentostatin (Nipent) : 2 outcomes 1 study in 3 results : FDA 2 Generic
  10. Prednisolone (Predate) : 2 outcomes in 7 results : FDA 55 Generic
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Diseases Related to Waldenstrom Macroglobulinemia

  1. Multiple Myeloma
  2. Lymphoma (Lymphomas)
  3. Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
  4. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
  5. Hairy Cell Leukemia
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Key Therapies for Waldenstrom Macroglobulinemia

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 6 outcomes 1 study in 46 results
  2. Plasmapheresis : 3 outcomes 3 studies in 31 results
  3. Stem Cell Transplantation : 3 outcomes in 17 results
  4. Splenectomy : 3 outcomes in 7 results
  5. Plasma Exchange : 1 outcome 1 study in 9 results
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