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Leukemia Summary

Description: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Also Known As: Leukemias

Networked: 41436 relevant articles (2260 outcomes, 5063 trials/studies) for this Disease

Key Drugs and Agents for Leukemia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cytarabine (Cytosar-U) : 114 outcomes 179 studies in 1037 results : FDA 13 Generic
  2. imatinib (Gleevec) : 74 outcomes 61 studies in 518 results : FDA 3
  3. Antigens : 63 outcomes 148 studies in 1768 results : IBA
  4. Cyclophosphamide (Cytoxan) : 56 outcomes 62 studies in 388 results : FDA 10 Generic
  5. Methotrexate (Mexate) : 42 outcomes 56 studies in 536 results : FDA 8 Generic
  6. Tretinoin (Retinoic Acid) : 39 outcomes 52 studies in 583 results : FDA 27 Generic
  7. Interleukin-2 (IL2) : 39 outcomes 42 studies in 303 results : IBA
  8. Etoposide (VP 16) : 35 outcomes 95 studies in 457 results : FDA 16 Generic
  9. Doxorubicin (Adriamycin) : 34 outcomes 89 studies in 665 results : FDA 12 Generic
  10. Vincristine (Oncovin) : 31 outcomes 48 studies in 351 results : FDA 17 Generic
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Diseases Related to Leukemia

  1. Neoplasms (Cancer)
  2. Lymphoma (Lymphomas)
  3. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
  4. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
  5. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
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Key Therapies for Leukemia

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 382 outcomes 392 studies in 3294 results
  2. Transplants (Transplant) : 257 outcomes 220 studies in 2669 results
  3. Bone Marrow Transplantation (Transplantation, Bone Marrow) : 150 outcomes 115 studies in 1422 results
  4. Transplantation (Transplant Recipients) : 127 outcomes 98 studies in 1214 results
  5. Hematopoietic Stem Cell Transplantation : 46 outcomes 48 studies in 514 results
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