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Keratoconus Summary

Description: A noninflammatory, usually bilateral protrusion of the cornea, the apex being displaced downward and nasally. It occurs most commonly in females at about puberty. The cause is unknown but hereditary factors may play a role. The -conus refers to the cone shape of the corneal protrusion. (From Dorland, 27th ed)

Key Drugs and Agents for Keratoconus

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Collagen : 47 outcomes 55 studies in 434 results : IBA
  2. Riboflavin (Vitamin B2) : 25 outcomes 29 studies in 191 results : FDA 8 Generic
  3. 1 Fuchs' endothelial Corneal dystrophy : 1 outcome 10 studies in 104 results : IBA
  4. Retinaldehyde (Retinal) : 1 outcome 2 studies in 21 results : IBA
  5. Nylons (Nylon) : 1 outcome in 9 results : IBA
  6. Hydrogel : 1 outcome in 8 results : IBA
  7. Mitomycin (Mitomycin-C) : 1 outcome in 5 results : FDA 7 Generic
  8. Cosmetics : 1 outcome in 3 results : IBA
  9. Cytidine Triphosphate (CTP) : 1 outcome in 2 results : IBA
  10. Adenosine Triphosphatases (ATPase) : 1 outcome in 2 results : IBA
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Diseases Related to Keratoconus

  1. Refractive Errors (Refractive Error)
  2. Astigmatism
  3. Pathologic Dilatation (Ectasia)
  4. Myopia
  5. Edema
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Key Therapies for Keratoconus

Efficacy Chart >>
  1. Corneal Transplantation (Keratoplasty) : 18 outcomes 39 studies in 468 results
  2. Laser In Situ Keratomileusis (LASIK) : 13 outcomes 9 studies in 129 results
  3. Penetrating Keratoplasty : 12 outcomes 45 studies in 421 results
  4. Contact Lenses : 9 outcomes 15 studies in 199 results
  5. Lasers (Laser) : 9 outcomes 13 studies in 92 results
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