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Chronic Idiopathic Jaundice (Dubin Johnson Syndrome) Summary

Description: A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.

Also Known As: Dubin Johnson Syndrome; Syndrome, Dubin-Johnson; Jaundice, Chronic Idiopathic; Hyperbilirubinemia 2; Chronic Idiopathic Jaundices Show All >>

Networked: 141 relevant articles (7 outcomes, 7 trials/studies) for this Disease

Key Drugs and Agents for Chronic Idiopathic Jaundice

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Phenobarbital (Luminal) : 1 outcome in 6 results : FDA 1
  2. Ursodeoxycholic Acid (Urso) : 1 outcome in 4 results : FDA 9 Generic
  3. Technetium Tc 99m Lidofenin : 1 outcome in 2 results : IBA
  4. Iron : 1 outcome in 2 results : IBA
  5. Rose Bengal : 1 outcome in 1 result : IBA
  6. Glycocholic Acid : 1 outcome in 1 result : IBA
  7. Bilirubin : 2 studies in 33 results : IBA
  8. Sulfobromophthalein (Sulfobromophthalein Sodium) : 1 study in 11 results : IBA
  9. Adenosine Triphosphate (ATP) : 1 study in 11 results : IBA
  10. P-glycoprotein 2 : 1 study in 11 results : IBA
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Diseases Related to Chronic Idiopathic Jaundice

  1. Jaundice
  2. Hereditary Hyperbilirubinemia (Rotor Syndrome)
  3. Liver Diseases (Liver Disease)
  4. Gilbert Disease
  5. Hepatocellular Carcinoma (Hepatoma)
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Key Therapies for Chronic Idiopathic Jaundice

Efficacy Chart >>
  1. Segmental Mastectomy (Lumpectomy) : 1 outcome in 1 result
  2. Lasers (Laser) : 1 study in 1 result
  3. Aftercare (After-Treatment) : 1 study in 1 result
  4. Hepatectomy : 3 results
  5. Transplants (Transplant) : 2 results
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