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Creutzfeldt-Jakob Syndrome
(Creutzfeldt-Jakob Disease)
Summary
Description:
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
Also Known As:
Creutzfeldt-Jakob Disease; Encephalopathy, Subacute Spongiform; Subacute Spongiform Encephalopathy; Syndrome, Creutzfeldt-Jakob; CJD (Creutzfeldt-Jakob Disease) Show All >>
Networked: 1557
relevant articles (8 outcomes,
88 trials/studies)
for this Disease
Key Drugs and Agents for Creutzfeldt-Jakob Syndrome
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
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14-3-3 Proteins (14-3-3 Protein)
:
2 outcomes 6 studies in 75 results
: IBA
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Acquired CJD
:
1 outcome 7 studies in 40 results
: IBA
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Prions
:
1 outcome 4 studies in 200 results
: IBA
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Amyloid (Amyloid Fibrils)
:
1 outcome 3 studies in 97 results
: IBA
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Growth Hormone (Somatotropin)
:
1 outcome 3 studies in 70 results
: IBA
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PrPSc Proteins
:
1 outcome 3 studies in 41 results
: IBA
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Paraffin
:
1 outcome 2 studies in 12 results
: IBA
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Formaldehyde (Formol)
:
1 outcome in 15 results
:
FDA 1
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Recombinant DNA (Recombinant DNA Research)
:
1 outcome in 1 result
: IBA
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Codon (Codons)
:
8 studies in 195 results
: IBA
Show All >>
Diseases Related to Creutzfeldt-Jakob Syndrome
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Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
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Scrapie
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Bovine Spongiform Encephalopathy (Mad Cow Disease)
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Kuru
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Alzheimer Disease (Alzheimer's Disease)
Show All >>
Key Therapies for Creutzfeldt-Jakob Syndrome
Efficacy Chart >>
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Homologous Transplantation (Allograft)
:
2 outcomes in 7 results
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Blood Transfusion (Blood Transfusions)
:
5 studies in 79 results
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Transplants (Transplant)
:
1 study in 86 results
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Nursing Care
:
1 study in 4 results
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Lenses
:
1 study in 1 result
Show All >>
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