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Ivermectin (Mectizan) Summary

Description: A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.

Also Known As: Mectizan; Stromectol; Eqvalan; Ivomec; MK-933 Show All >>

Networked: 1879 relevant articles (369 outcomes, 321 trials/studies) for this Drug

Key Diseases for which Ivermectin is Relevant

  1. Infection : 120 outcomes 80 studies in 477 results
  2. Scabies (Sarcoptic Mange) : 45 outcomes 33 studies in 208 results
  3. Onchocerciasis : 43 outcomes 91 studies in 554 results
  4. Body Weight (Weight, Body) : 35 outcomes 24 studies in 253 results
  5. Strongyloidiasis : 21 outcomes 9 studies in 76 results
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Drugs Related to Ivermectin

  1. Diethylcarbamazine (Hetrazan)
  2. Albendazole (Albenza)
  3. doramectin
  4. Ivermectin (Mectizan)
  5. Permethrin (Ambush)
  6. milbemycin (moxidectin)
  7. Levamisole (Decaris)
  8. Fenbendazole
  9. Praziquantel (Biltricide)
  10. Carbon Monoxide
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Therapies Related to Ivermectin

  1. Aftercare (After-Treatment)
  2. Injections
  3. Drug Therapy (Chemotherapy)
  4. Subcutaneous Injections
  5. Combination Drug Therapy (Combination Chemotherapy)
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