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Immunoproliferative Small Intestinal Disease Summary

Description: A condition that is caused by HYPERPLASIA of LYMPHOCYTES in the small intestine (INTESTINE, SMALL) and the mesenteric LYMPH NODES. These lymphocytes produce an anomalous alpha heavy chain protein. Generally, these IPSID patients have either concurrent LYMPHOMA or develop lymphoma within a few years. The disease was first described in the Mediterranean region and is characterized by malabsorption; WEIGHT LOSS; DIARRHEA; and STEATORRHEA.

Also Known As: Disease, alpha-Chain; Diseases, alpha-Chain; Mediterranean Lymphoma; alpha Chain Disease; alpha-Chain Diseases Show All >>

Networked: 69 relevant articles (7 outcomes, 7 trials/studies) for this Disease

Key Drugs and Agents for Immunoproliferative Small Intestinal Disease

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Anti-Bacterial Agents (Antibiotics) : 2 outcomes 1 study in 7 results : IBA
  2. Tetracycline (Achromycin) : 2 outcomes in 5 results : FDA 62 Generic
  3. Cyclophosphamide (Cytoxan) : 1 outcome in 3 results : FDA 10 Generic
  4. Vincristine (Oncovin) : 1 outcome in 2 results : FDA 17 Generic
  5. Prednisolone (Predate) : 1 outcome in 2 results : FDA 55 Generic
  6. Sulfasalazine (Azulfidine) : 1 outcome in 1 result : FDA 16 Generic
  7. Melphalan (Alkeran) : 1 outcome in 1 result : FDA 2 Generic
  8. Mebendazole (Vermin) : 1 outcome in 1 result : FDA 2
  9. OPPA protocol : 1 outcome in 1 result : IBA
  10. Immunoglobulin A (IgA) : 2 studies in 16 results : IBA
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Diseases Related to Immunoproliferative Small Intestinal Disease

  1. Lymphoma (Lymphomas)
  2. Non-Hodgkin Lymphoma (Lymphosarcoma)
  3. Immunoproliferative Small Intestinal Disease
  4. Heavy Chain Disease
  5. Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
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Key Therapies for Immunoproliferative Small Intestinal Disease

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 1 outcome in 6 results
  2. Laparotomy : 2 results
  3. Combination Drug Therapy (Combination Chemotherapy) : 2 results
  4. Transplants (Transplant) : 1 result
  5. Pancreaticoduodenectomy : 1 result

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