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Dysgerminoma Summary

Description: A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)

Also Known As: Disgerminomas; Dysgerminomas; Disgerminoma

Networked: 315 relevant articles (21 outcomes, 21 trials/studies) for this Disease

Key Drugs and Agents for Dysgerminoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cisplatin (Platino) : 3 outcomes 1 study in 15 results : FDA 6 Generic
  2. Cyclophosphamide (Cytoxan) : 2 outcomes in 7 results : FDA 10 Generic
  3. Keratins (Keratin) : 1 outcome 1 study in 4 results : IBA
  4. alpha-Fetoproteins (AFP) : 1 outcome in 19 results : IBA
  5. Platinum : 1 outcome in 4 results : IBA
  6. Periodic Acid : 1 outcome in 2 results : IBA
  7. Hematoxylin (Haematoxylon) : 1 outcome in 2 results : IBA
  8. Eosine Yellowish-(YS) (Eosin) : 1 outcome in 2 results : IBA
  9. Pyronine : 1 outcome in 1 result : IBA
  10. Methyl Green (Green, Light) : 1 outcome in 1 result : IBA
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Diseases Related to Dysgerminoma

  1. Neoplasms (Cancer)
  2. Seminoma
  3. Teratoma (Teratoid Tumor)
  4. Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
  5. Endodermal Sinus Tumor (Endodermal Sinus Tumors)
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Key Therapies for Dysgerminoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 14 outcomes 6 studies in 81 results
  2. Radiotherapy : 6 outcomes in 40 results
  3. Ovariectomy (Oophorectomy) : 1 outcome in 20 results
  4. Hysterectomy : 1 outcome in 8 results
  5. Combination Drug Therapy (Combination Chemotherapy) : 1 outcome in 5 results
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