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Patent Ductus Arteriosus Summary

Description: A congenital heart defect characterized by the persistent opening of fetal DUCTUS ARTERIOSUS that connects the PULMONARY ARTERY to the descending aorta (AORTA, DESCENDING) allowing unoxygenated blood to bypass the lung and flow to the PLACENTA. Normally, the ductus is closed shortly after birth.

Also Known As: Ductus Arteriosus, Patent; Patency of the Ductus Arteriosus; Patent Ductus Arteriosus Familial

Networked: 2309 relevant articles (100 outcomes, 192 trials/studies) for this Disease

Key Drugs and Agents for Patent Ductus Arteriosus

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Indomethacin (Indometacin) : 30 outcomes 69 studies in 459 results : FDA 56 Generic
  2. Ibuprofen (Motrin) : 22 outcomes 29 studies in 182 results : FDA 197 Generic
  3. Acetaminophen (Paracetamol) : 8 outcomes 1 study in 30 results : FDA 409 Generic
  4. beta-apocarotenoid-14',13'-dioxygenase (ADO) : 4 outcomes 6 studies in 24 results : IBA
  5. Alprostadil (Muse) : 4 outcomes 2 studies in 40 results : FDA 8 Generic
  6. Furosemide (Lasix) : 4 outcomes 2 studies in 22 results : FDA 57 Generic
  7. Oxygen : 3 outcomes 14 studies in 121 results : IBA
  8. Steroids : 2 outcomes 3 studies in 32 results : IBA
  9. nitinol : 2 outcomes 1 study in 14 results : IBA
  10. ROP : 2 outcomes in 49 results : IBA
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Diseases Related to Patent Ductus Arteriosus

  1. Hemorrhage
  2. Birth Weight (Birth Weights)
  3. Pulmonary Hypertension (Ayerza Syndrome)
  4. Pneumothorax
  5. Bronchopulmonary Dysplasia
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Key Therapies for Patent Ductus Arteriosus

Efficacy Chart >>
  1. Ligation : 11 outcomes 33 studies in 477 results
  2. Catheters : 4 outcomes 6 studies in 103 results
  3. Septal Occluder Device : 3 outcomes in 16 results
  4. Artificial Respiration (Mechanical Ventilation) : 2 outcomes 10 studies in 86 results
  5. Thoracotomy : 1 outcome 6 studies in 51 results
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