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Diabetic Nephropathies (Diabetic Nephropathy) Summary

Description: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Also Known As: Diabetic Nephropathy; Nephropathy, Diabetic; Diabetic Kidney Disease; Intracapillary Glomerulosclerosis; Kimmelstiel-Wilson Disease Show All >>

Networked: 7740 relevant articles (530 outcomes, 1404 trials/studies) for this Disease

Key Drugs and Agents for Diabetic Nephropathies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Streptozocin (Streptozotocin) : 39 outcomes 91 studies in 407 results : FDA 1
  2. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors) : 32 outcomes 64 studies in 332 results : IBA
  3. Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme) : 31 outcomes 75 studies in 342 results : IBA
  4. Insulin (Novolin) : 18 outcomes 64 studies in 436 results : FDA 2
  5. Angiotensin Receptor Antagonists : 18 outcomes 36 studies in 137 results : IBA
  6. Glucose (Dextrose) : 16 outcomes 51 studies in 424 results : FDA 175 Generic
  7. Creatinine : 15 outcomes 41 studies in 298 results : IBA
  8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 15 outcomes 21 studies in 139 results : IBA
  9. Angiotensin II : 14 outcomes 55 studies in 193 results : IBA
  10. Blood Glucose (Blood Sugar) : 13 outcomes 13 studies in 118 results : IBA
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Diseases Related to Diabetic Nephropathies

  1. Proteinuria
  2. Hypertension (High Blood Pressure)
  3. Albuminuria
  4. Chronic Kidney Failure (Chronic Renal Failure)
  5. Heart Failure
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Key Therapies for Diabetic Nephropathies

Efficacy Chart >>
  1. Kidney Transplantation : 7 outcomes 4 studies in 148 results
  2. Transplantation (Transplant Recipients) : 6 outcomes 6 studies in 112 results
  3. Pancreas Transplantation : 4 outcomes 5 studies in 50 results
  4. Renal Dialysis (Hemodialysis) : 3 outcomes 13 studies in 167 results
  5. Protein-Restricted Diet (Diet, Protein Restricted) : 3 outcomes 8 studies in 47 results
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