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Dandy-Walker Syndrome (Dandy Walker Malformation) Summary

Description: A congenital abnormality of the central nervous system marked by failure of the midline structures of the cerebellum to develop, dilation of the fourth ventricle, and upward displacement of the transverse sinuses, tentorium, and torcula. Clinical features include occipital bossing, progressive head enlargement, bulging of anterior fontanelle, papilledema, ataxia, gait disturbances, nystagmus, and intellectual compromise. (From Menkes, Textbook of Child Neurology, 5th ed, pp294-5)

Also Known As: Dandy Walker Malformation; Syndrome, Dandy-Walker; Dandy-Walker Syndrome, Familial; Dandy Walker Syndrome; Dandy Walker Syndrome, Familial Show All >>

Networked: 161 relevant articles (0 outcomes, 6 trials/studies) for this Disease

Key Drugs and Agents for Dandy-Walker Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Dandy Walker variant : 3 studies in 27 results : IBA
  2. Neurocutaneous melanosis : 1 study in 15 results : IBA
  3. tranilast (N 5') : 1 study in 2 results : IBA
  4. Renal hepatic pancreatic dysplasia Dandy Walker cyst : 6 results : IBA
  5. tetrasomy 9p Chromosome 9 : 4 results : IBA
  6. Molybdenum cofactor deficiency : 4 results : IBA
  7. trisomy Chromosome 9 : 3 results : IBA
  8. Keratitis, Ichthyosis, and Deafness (KID) Syndrome : 3 results : IBA
  9. Meckel syndrome type 1 : 3 results : IBA
  10. Warfarin (Coumadin) : 2 results : FDA 21 Generic
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Diseases Related to Dandy-Walker Syndrome

  1. Cysts
  2. Hydrocephalus (Hydrocephaly)
  3. Chromosome Aberrations (Chromosome Abnormalities)
  4. Arachnoid Cysts (Arachnoid Cyst)
  5. Cleft Palate (Palate, Cleft)
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Key Therapies for Dandy-Walker Syndrome

Efficacy Chart >>
  1. Colonic Pouches (S Pouch) : 3 studies in 15 results
  2. Ventriculoperitoneal Shunt : 7 results
  3. Ventriculostomy : 4 results
  4. Catheters : 3 results
  5. Decompression : 3 results
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