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Cisplatin (Platino) Summary

Description: An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.

Also Known As: Platino; cis-Platinum; Biocisplatinum; Dichlorodiammineplatinum; NSC-119875 Show All >>

Networked: 27682 relevant articles (3052 outcomes, 7049 trials/studies) for this Drug

Key Diseases for which Cisplatin is Relevant

  1. Neoplasms (Cancer) : 816 outcomes 1447 studies in 8936 results
  2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) : 248 outcomes 1018 studies in 2167 results
  3. Carcinoma (Carcinomatosis) : 240 outcomes 694 studies in 3027 results
  4. Vomiting : 204 outcomes 241 studies in 1096 results
  5. Ovarian Neoplasms (Ovarian Cancer) : 187 outcomes 515 studies in 1993 results
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Drugs Related to Cisplatin

  1. Fluorouracil (Carac)
  2. gemcitabine
  3. Etoposide (VP 16)
  4. Doxorubicin (Adriamycin)
  5. Paclitaxel (Taxol)
  6. docetaxel (Taxotere)
  7. Carboplatin (JM8)
  8. Cyclophosphamide (Cytoxan)
  9. Ifosfamide
  10. Platinum
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Therapies Related to Cisplatin

  1. Drug Therapy (Chemotherapy)
  2. Combination Drug Therapy (Combination Chemotherapy)
  3. Radiotherapy
  4. Heterologous Transplantation (Xenotransplantation)
  5. Adjuvant Chemotherapy
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