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C-Peptide Summary

Description: The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.

Also Known As: C-Peptide, Proinsulin; Connecting Peptide; C Peptide; C Peptide, Proinsulin; Proinsulin C Peptide Show All >>

Networked: 2442 relevant articles (103 outcomes, 269 trials/studies) for this Bio-Agent

Key Diseases for which C-Peptide is Relevant

  1. Type 1 Diabetes Mellitus (Autoimmune Diabetes) : 19 outcomes 42 studies in 221 results
  2. Insulin Resistance : 12 outcomes 26 studies in 372 results
  3. Type 2 Diabetes Mellitus (MODY) : 8 outcomes 29 studies in 213 results
  4. Hyperglycemia : 8 outcomes 12 studies in 148 results
  5. Weight Loss (Weight Reduction) : 8 outcomes 3 studies in 45 results
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Drugs Related to C-Peptide

  1. Insulin (Novolin)
  2. Glucose (Dextrose)
  3. Glucagon (Glukagon)
  4. Blood Glucose (Blood Sugar)
  5. Proinsulin
  6. Insulin-Like Growth Factor I (IGF-1)
  7. Triglycerides (Triacylglycerol)
  8. Glyburide (Glibenclamide)
  9. Hemoglobins (Hemoglobin)
  10. Arginine (L-Arginine)
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Therapies Related to C-Peptide

  1. Transplantation (Transplant Recipients)
  2. Transplants (Transplant)
  3. Kidney Transplantation
  4. Plasmapheresis
  5. Female Contraceptive Devices (Vaginal Ring)
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