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Buprenorphine (Subutex) Summary

Description: A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.

Also Known As: Subutex; Buprenex; 6029-M; Buprenorphine Hydrochloride; Buprex Show All >>

Networked: 1602 relevant articles (183 outcomes, 291 trials/studies) for this Drug

Key Diseases for which Buprenorphine is Relevant

  1. Pain (Aches) : 85 outcomes 123 studies in 580 results
  2. Neoplasms (Cancer) : 17 outcomes 27 studies in 92 results
  3. Postoperative Pain : 17 outcomes 19 studies in 132 results
  4. Heroin Dependence (Heroin Abuse) : 14 outcomes 15 studies in 87 results
  5. Substance Withdrawal Syndrome (Withdrawal Symptoms) : 14 outcomes 14 studies in 93 results
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Drugs Related to Buprenorphine

  1. Methadone (Dolophine)
  2. Morphine (MS Contin)
  3. Fentanyl (Sublimaze)
  4. Naloxone (Narcan)
  5. Opioid Analgesics (Opioids)
  6. Bupivacaine (Bupivacaine Hydrochloride)
  7. Acetaminophen (Paracetamol)
  8. Tramadol
  9. Meperidine (Pethidine)
  10. Cocaine (Cocaine HCl)
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Therapies Related to Buprenorphine

  1. Analgesia
  2. Transdermal Patch
  3. Thoracotomy
  4. Drug Therapy (Chemotherapy)
  5. Injections
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