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Brain Injuries (Brain Injury) Summary

Description: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Also Known As: Brain Injury; Traumatic Brain Injury; Brain Trauma; TBI (Traumatic Brain Injury); Brain Injury, Traumatic Show All >>

Networked: 13861 relevant articles (797 outcomes, 2389 trials/studies) for this Disease

Key Drugs and Agents for Brain Injuries

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Progesterone : 23 outcomes 42 studies in 160 results : FDA 11 Generic
  2. Oxygen : 20 outcomes 69 studies in 497 results : IBA
  3. Biological Markers (Surrogate Marker) : 17 outcomes 68 studies in 397 results : IBA
  4. Melatonin : 15 outcomes 19 studies in 90 results : IBA
  5. N-Methylaspartate (NMDA) : 14 outcomes 48 studies in 234 results : IBA
  6. Erythropoietin : 12 outcomes 31 studies in 144 results : FDA 1
  7. Estradiol (Estrace) : 12 outcomes 8 studies in 50 results : FDA 44 Generic
  8. Brain-Derived Neurotrophic Factor (BDNF) : 11 outcomes 20 studies in 102 results : IBA
  9. Glutamic Acid (Glutamate) : 9 outcomes 34 studies in 331 results : FDA 7
  10. Cyclosporine (Ciclosporin) : 9 outcomes 8 studies in 45 results : FDA 20 Generic
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Diseases Related to Brain Injuries

  1. Stroke (Strokes)
  2. Ischemia
  3. Brain Ischemia (Cerebral Ischemia)
  4. Brain Injuries (Brain Injury)
  5. Hypothermia
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Key Therapies for Brain Injuries

Efficacy Chart >>
  1. Transplantation (Transplant Recipients) : 20 outcomes 25 studies in 167 results
  2. Resuscitation : 14 outcomes 31 studies in 260 results
  3. Decompressive Craniectomy : 8 outcomes 38 studies in 232 results
  4. Induced Hypothermia : 6 outcomes 9 studies in 48 results
  5. Hyperbaric Oxygenation : 6 outcomes 8 studies in 50 results
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