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Baclofen Summary

Description: A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUCSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.

Also Known As: ASTA Medica Brand of Baclofen; Alphapharm Brand of Baclofen; Apo-Baclofen; Apotex Brand of Baclofen; Ashbourne Brand of Baclofen Show All >>

Networked: 1699 relevant articles (242 outcomes, 227 trials/studies) for this Drug

Key Diseases for which Baclofen is Relevant

  1. Pain (Aches) : 25 outcomes 15 studies in 133 results
  2. Dystonia (Limb Dystonia) : 24 outcomes 12 studies in 106 results
  3. Spasm (Spasms) : 24 outcomes 5 studies in 103 results
  4. Cerebral Palsy (Spastic Diplegia) : 18 outcomes 31 studies in 152 results
  5. Spinal Cord Injuries (Spinal Cord Injury) : 13 outcomes 8 studies in 87 results
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Drugs Related to Baclofen

  1. gamma-Aminobutyric Acid (GABA)
  2. GABA-B Receptor Agonists
  3. GABA Agonists (GABA Receptor Agonists)
  4. gabapentin (Neurontin)
  5. Carbamazepine (Tegretol)
  6. tizanidine (Zanaflex)
  7. Morphine (MS Contin)
  8. Clonidine (ST 155)
  9. Diazepam (Valium)
  10. Carbon Monoxide
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Therapies Related to Baclofen

  1. Injections
  2. Oral Administration
  3. Transcutaneous Electric Nerve Stimulation (TENS)
  4. Drug Therapy (Chemotherapy)
  5. Analgesia
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