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Apolipoproteins E (ApoE) Summary

Description: A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.

Also Known As: ApoE; Apo E; Apo E Isoproteins; Apolipoprotein E Isoproteins; Apoprotein (E) Show All >>

Networked: 7767 relevant articles (236 outcomes, 1472 trials/studies) for this Bio-Agent

Key Diseases for which Apolipoproteins E is Relevant

  1. Atherosclerosis : 84 outcomes 376 studies in 2134 results
  2. Alzheimer Disease (Alzheimer's Disease) : 24 outcomes 262 studies in 2088 results
  3. Atherosclerotic Plaque (Atheroma) : 11 outcomes 57 studies in 494 results
  4. Dementia (Dementias) : 10 outcomes 132 studies in 657 results
  5. Hyperlipidemias (Hyperlipidemia) : 10 outcomes 29 studies in 218 results
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Drugs Related to Apolipoproteins E

  1. Apolipoproteins
  2. Cholesterol
  3. Lipoproteins (Lipoprotein)
  4. Peptides
  5. Amyloid (Amyloid Fibrils)
  6. Apolipoproteins E (ApoE)
  7. Apolipoprotein E4
  8. Antibodies
  9. LDL Receptors (LDL Receptor)
  10. Apolipoprotein A-I (Apolipoprotein A1)
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Therapies Related to Apolipoproteins E

  1. Ligation
  2. Transplantation (Transplant Recipients)
  3. Transplants (Transplant)
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  5. Intramuscular Injections
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