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Local Anesthetics Summary

Description: Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.

Also Known As: Anesthetics, Local; Anesthetics, Conduction Blocking; Conduction Blocking Anesthetics; Anesthetics, Conduction-Blocking; Conduction-Blocking Anesthetics

Networked: 1332 relevant articles (103 outcomes, 117 trials/studies) for this Bio-Agent

Key Diseases for which Local Anesthetics is Relevant

  1. Pain (Aches) : 54 outcomes 48 studies in 470 results
  2. Postoperative Pain : 17 outcomes 13 studies in 115 results
  3. Wounds and Injuries (Trauma) : 8 outcomes 9 studies in 75 results
  4. Neoplasms (Cancer) : 6 outcomes 8 studies in 48 results
  5. Neuralgia (Stump Neuralgia) : 5 outcomes 5 studies in 37 results
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Drugs Related to Local Anesthetics

  1. Opioid Analgesics (Opioids)
  2. Lidocaine (Xylocaine)
  3. Steroids
  4. Anticonvulsants (Antiepileptic Drugs)
  5. Bupivacaine (Bupivacaine Hydrochloride)
  6. Analgesics (Analgesic Drugs)
  7. Antidepressive Agents (Antidepressants)
  8. levobupivacaine (Chirocaine)
  9. Epinephrine (Adrenaline)
  10. ropivacaine (Naropin)
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Therapies Related to Local Anesthetics

  1. Analgesia
  2. Injections
  3. Catheters
  4. Nerve Block (Nerve Blocks)
  5. Anesthesia
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