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Amyloidosis Summary

Description: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

Also Known As: Amyloidoses

Networked: 7515 relevant articles (352 outcomes, 599 trials/studies) for this Disease

Key Drugs and Agents for Amyloidosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Amyloid (Amyloid Fibrils) : 64 outcomes 200 studies in 2727 results : IBA
  2. Colchicine : 45 outcomes 17 studies in 228 results : FDA 13 Generic
  3. Melphalan (Alkeran) : 31 outcomes 23 studies in 176 results : FDA 2 Generic
  4. Dexamethasone (Maxidex) : 22 outcomes 19 studies in 101 results : FDA 77 Generic
  5. bortezomib (Velcade) : 14 outcomes 10 studies in 69 results : FDA 1
  6. tocilizumab : 11 outcomes 1 study in 26 results : FDA 2
  7. Cyclophosphamide (Cytoxan) : 10 outcomes 8 studies in 34 results : FDA 10 Generic
  8. Prealbumin (Transthyretin) : 9 outcomes 38 studies in 715 results : IBA
  9. Dimethyl Sulfoxide (DMSO) : 9 outcomes 9 studies in 65 results : FDA 3 Generic
  10. Immunoglobulin Light Chains (Immunoglobulin Light Chain) : 8 outcomes 24 studies in 389 results : IBA
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Diseases Related to Amyloidosis

  1. Familial Mediterranean Fever (Periodic Disease)
  2. Rheumatoid Arthritis
  3. Nephrotic Syndrome (Syndrome, Nephrotic)
  4. Proteinuria
  5. Multiple Myeloma
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Key Therapies for Amyloidosis

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 27 outcomes 13 studies in 177 results
  2. Stem Cell Transplantation : 23 outcomes 14 studies in 160 results
  3. Transplants (Transplant) : 10 outcomes 11 studies in 152 results
  4. Liver Transplantation : 10 outcomes 1 study in 100 results
  5. Renal Dialysis (Hemodialysis) : 6 outcomes 18 studies in 302 results
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