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Alkylating Agents Summary

Description: Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.

Also Known As: Alkylators; Agents, Alkylating

Networked: 1837 relevant articles (97 outcomes, 160 trials/studies) for this Bio-Agent

Key Diseases for which Alkylating Agents is Relevant

  1. Neoplasms (Cancer) : 23 outcomes 58 studies in 602 results
  2. Multiple Myeloma : 7 outcomes 8 studies in 67 results
  3. Breast Neoplasms (Breast Cancer) : 6 outcomes 12 studies in 68 results
  4. Glioblastoma (Glioblastoma Multiforme) : 5 outcomes 5 studies in 55 results
  5. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) : 5 outcomes 4 studies in 42 results
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Drugs Related to Alkylating Agents

  1. Cyclophosphamide (Cytoxan)
  2. DNA (Deoxyribonucleic Acid)
  3. temozolomide (Temodar)
  4. Vincristine (Oncovin)
  5. Doxorubicin (Adriamycin)
  6. Ifosfamide
  7. Carmustine (FIVB)
  8. Anthracyclines
  9. Chlorambucil (Leukeran)
  10. Adrenal Cortex Hormones (Corticosteroids)
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Therapies Related to Alkylating Agents

  1. Drug Therapy (Chemotherapy)
  2. Radiotherapy
  3. Combination Drug Therapy (Combination Chemotherapy)
  4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  5. Stem Cell Transplantation
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