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Akinetic Mutism (Coma Vigil) Summary

Description: A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)

Also Known As: Coma Vigil; Akinetic Autism; Coma Vigilans; Akinetic Mutisms; Autism, Akinetic Show All >>

Networked: 75 relevant articles (11 outcomes, 4 trials/studies) for this Disease

Key Drugs and Agents for Akinetic Mutism

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Bromocriptine (Parlodel) : 6 outcomes in 16 results : FDA 8 Generic
  2. Dopamine Agonists (Dopamine Agonist) : 2 outcomes in 7 results : IBA
  3. zolpidem (Ambien) : 1 outcome 1 study in 1 result : FDA 29 Generic
  4. Baclofen : 1 outcome in 3 results : FDA 31 Generic
  5. Cyclosporine (Ciclosporin) : 1 outcome in 2 results : FDA 20 Generic
  6. Trihexyphenidyl (Artane) : 1 outcome in 2 results : FDA 16 Generic
  7. Levodopa (L Dopa) : 1 outcome in 2 results : FDA 31 Generic
  8. GABA Agonists (GABA Receptor Agonists) : 1 outcome in 1 result : IBA
  9. Metoprolol (Lopressor) : 1 outcome in 1 result : FDA 37 Generic
  10. Magnesium Sulfate (Sulfate, Magnesium) : 1 outcome in 1 result : FDA 7 Generic
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Diseases Related to Akinetic Mutism

  1. Stroke (Strokes)
  2. Neurologic Manifestations (Neurological Manifestations)
  3. Movement Disorders (Movement Disorder)
  4. Bruxism
  5. Poisoning
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Key Therapies for Akinetic Mutism

Efficacy Chart >>
  1. Enteral Nutrition (Feeding, Tube) : 4 results
  2. Aftercare (After-Treatment) : 4 results
  3. Active Euthanasia : 2 results
  4. Transplants (Transplant) : 2 results
  5. Chemoprevention : 1 result
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