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Acromegaly Summary

Description: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)

Also Known As: Inappropriate GH Secretion Syndrome (Acromegaly); Hypersecretion Syndrome, Somatotropin (Acromegaly); Hypersecretion Syndromes, Somatotropin (Acromegaly); Somatotropin Hypersecretion Syndromes (Acromegaly); Syndrome, Somatotropin Hypersecretion (Acromegaly) Show All >>

Networked: 3656 relevant articles (401 outcomes, 480 trials/studies) for this Disease

Key Drugs and Agents for Acromegaly

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Insulin-Like Growth Factor I (IGF-1) : 95 outcomes 87 studies in 718 results : IBA
  2. Octreotide (Sandostatin) : 92 outcomes 98 studies in 508 results : FDA 14 Generic
  3. Somatostatin (Somatotropin Release-Inhibiting Factor) : 79 outcomes 61 studies in 571 results : IBA
  4. Growth Hormone (Somatotropin) : 47 outcomes 81 studies in 1145 results : IBA
  5. lanreotide (Somatuline) : 47 outcomes 40 studies in 146 results : FDA 1
  6. Glucose (Dextrose) : 39 outcomes 27 studies in 321 results : FDA 175 Generic
  7. pegvisomant : 36 outcomes 39 studies in 170 results : FDA 2 Generic
  8. Insulin (Novolin) : 22 outcomes 37 studies in 362 results : FDA 2
  9. Bromocriptine (Parlodel) : 13 outcomes 17 studies in 203 results : FDA 8 Generic
  10. pasireotide : 13 outcomes 17 studies in 36 results : IBA
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Diseases Related to Acromegaly

  1. Neoplasms (Cancer)
  2. Pituitary Neoplasms (Pituitary Adenoma)
  3. Prolactinoma (Prolactinomas)
  4. Adenoma (Adenomas)
  5. Hypopituitarism (Sheehan's Syndrome)
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Key Therapies for Acromegaly

Efficacy Chart >>
  1. Radiotherapy : 27 outcomes 6 studies in 186 results
  2. Aftercare (After-Treatment) : 8 outcomes 10 studies in 78 results
  3. Pituitary Irradiation : 7 outcomes 1 study in 33 results
  4. Drug Therapy (Chemotherapy) : 6 outcomes 3 studies in 44 results
  5. Injections : 6 outcomes 3 studies in 28 results
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