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tegaserod (Zelnorm) Summary

Description: a nonbenzamide 5-hydroxytryptamine(4) agonist; used in treatment of irritable bowel syndrome; marketing suspended 2007 in US due to higher incidence of MI, stroke, and unstable angina; structure given in first source

Also Known As: Zelnorm; 5-methoxyindol-3-carboxaldehyde amino(pentylamino)methylenehydrazone hydrogen maleate; HTF 919; Novartis brand of tegaserod maleate; SDZ HTF 919 Show All >>

Networked: 231 relevant articles (59 outcomes, 61 trials/studies) for this Drug

Key Diseases for which tegaserod is Relevant

  1. Constipation : 44 outcomes 37 studies in 144 results
  2. Irritable Bowel Syndrome (Syndrome, Irritable Bowel) : 23 outcomes 25 studies in 102 results
  3. Abdominal Pain (Pain, Abdominal) : 8 outcomes 9 studies in 32 results
  4. Pain (Aches) : 5 outcomes 1 study in 16 results
  5. Parkinson Disease (Parkinson's Disease) : 3 outcomes 2 studies in 4 results
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Drugs Related to tegaserod

  1. Serotonin (5 Hydroxytryptamine)
  2. 5-HT4 Serotonin Receptors
  3. tegaserod (Zelnorm)
  4. alosetron (Lotronex)
  5. Serotonin 5-HT4 Receptor Agonists
  6. Cisapride (Propulsid)
  7. Glycopyrrolate (Glycopyrronium Bromide)
  8. Neostigmine (Neostigmine Bromide)
  9. lubiprostone
  10. prucalopride
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Therapies Related to tegaserod

  1. Retreatment
  2. Chinese Traditional Medicine (Traditional Chinese Medicine)
  3. Stents
  4. Renal Dialysis (Hemodialysis)
  5. Cholecystectomy
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