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Agammaglobulinaemia tyrosine kinase (Bruton's tyrosine kinase) Summary

Description: has been sequenced; a cytoplasmic tyrosine kinase; mutation in BTK in human causes X-linked AGAMMAGLOBULINEMIA type 1 (XLA); plays a vital role in B-cell ontogeny; RefSeq NM_013482 (mouse), NM_000061 (human)

Also Known As: Bruton's tyrosine kinase; AGMX1 protein, human; ATK protein, human; B cell progenitor kinase; BPK protein, human Show All >>

Networked: 137 relevant articles (5 outcomes, 9 trials/studies) for this Bio-Agent

Key Diseases for which Agammaglobulinaemia tyrosine kinase is Relevant

  1. Lymphoma (Lymphomas) : 3 outcomes 3 studies in 12 results
  2. Neoplasms (Cancer) : 1 outcome 1 study in 18 results
  3. B-Cell Lymphoma (Lymphoma, B Cell) : 1 outcome 1 study in 4 results
  4. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) : 1 outcome in 13 results
  5. Experimental Arthritis : 1 outcome in 3 results
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Drugs Related to Agammaglobulinaemia tyrosine kinase

  1. Proteasome Endopeptidase Complex (Proteasome)
  2. Immunologic Factors (Immunomodulators)
  3. Phosphotransferases (Kinase)
  4. temsirolimus
  5. Bruton type agammaglobulinemia
  6. Syk kinase
  7. Protein-Tyrosine Kinases (Tyrosine Kinase)
  8. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
  9. Janus Kinase 3
  10. Sirolimus (Rapamycin)
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Therapies Related to Agammaglobulinaemia tyrosine kinase

  1. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Immunotherapy
  4. Oral Administration

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