continuous erythropoietin receptor activator FDA Link

a third-generation erythropoietic beta molecule created by integrating a large polymer chain into the molecule, thus increasing the molecular weight to twice that of epoetin at approximately 60 kDa; the methoxy-polyethylene glycol polymer chain is integrated via amide bonds between the N-terminal amino group or the e-amino group of lysine (predominantly lysine-52 or lysine-45), using a single succinimidyl butanoic acid linker; an erythropoiesis-stimulating agent for the treatment of anemia

Also Known As:

CERA (erythropoietin receptor activator); Mircera; epoetin beta pegol; methoxy polyethylene glycol-epoetin beta

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Colony-Stimulating Factors: 1599
      - Erythropoietin: 12227
        continuous erythropoietin receptor activator: 121
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1599
        Erythropoietin: 12227
        continuous erythropoietin receptor activator: 121
  - Glycoproteins: 24834
    - Colony-Stimulating Factors: 1599
      - Erythropoietin: 12227
        continuous erythropoietin receptor activator: 121
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Hematopoietic Cell Growth Factors: 13
        Colony-Stimulating Factors: 1599
        Erythropoietin: 12227
        continuous erythropoietin receptor activator: 121
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Hematopoietic Cell Growth Factors: 13
      - Colony-Stimulating Factors: 1599
        Erythropoietin: 12227
        continuous erythropoietin receptor activator: 121
Organic Chemicals: 133
- Alcohols: 595
  - Glycols: 38
    - Ethylene Glycols: 8
      - Polyethylene Glycols: 3865
        continuous erythropoietin receptor activator: 121
Macromolecular Substances: 97
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - continuous erythropoietin receptor activator: 121
Biomedical and Dental Materials
- Polymers: 13051
  - Polyethylene Glycols: 3865
    - continuous erythropoietin receptor activator: 121
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - Polyethylene Glycols: 3865
        continuous erythropoietin receptor activator: 121

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