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Antibiotics produced by Streptomyces ficellus II. Feldamycin and nojirimycin.

Abstract
Feldamycin, a new antibacterial agent, and nojirimycin, a previously described antibiotic have been isolated from cultures of Streptomyces ficellus. Feldamycin, C17H25N7O5, is an amphoteric compound which inhibits a variety of bacteria in vitro but is found to be ineffective in the treatment of experimental bacterial infections in mice. Nojirimycin (5-amino-5-deoxy-D-glucose) has been isolated previously from cultures of several species of streptomycetes.
AuthorsA D Argoudelis, F Reusser, S A Mizsak, L Baczynskyj
JournalThe Journal of antibiotics (J Antibiot (Tokyo)) Vol. 29 Issue 10 Pg. 1007-14 (Oct 1976) ISSN: 0021-8820 [Print] England
PMID994320 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Antibiotics, Antineoplastic
Topics
  • Animals
  • Anti-Bacterial Agents (analysis, biosynthesis, pharmacology)
  • Antibiotics, Antineoplastic (therapeutic use)
  • Bacterial Infections (prevention & control)
  • Chemical Phenomena
  • Chemistry
  • Fermentation
  • Fungi (drug effects)
  • Leukemia L1210 (drug therapy)
  • Mice
  • Streptomyces (metabolism)
  • Viruses (drug effects)

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