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Pericardial tamponade as the first manifestation of dermatopolymyositis.

Abstract
Pericardial involvement in polymyositis and dermatomyositis (PM/DM) is rare, usually asymptomatic and exceptionally part of the initial presentation. We describe a 37-year-old patient hospitalized for overt acute pericarditis, revealing dermatomyositis, which to our knowledge has not been previously reported. Pericardial puncture relieved the patient. The pericardial fluid was citrine yellow, exsudative, and mainly contained lymphocytes. Search for LE cells and anti-DNA antibodies was negative, whereas the antinuclear antibodies and the rheumatoid factor were present in the pericardial fluid. A biopsy of the pericardium showed a non-specific chronic inflammatory state and the search for an etiology was negative. There was no sign of tuberculosis, systemic lupus, nor neoplasia. Moreover bacteriological cultures and HIV serology were negative. After pericardiostomy associated with corticosteroid therapy at the dose of 1 mg/kg/day, outcome was good with a resolution of the pericarditis confirmed at one-year follow-up. Since pericardial tamponade, even though rare, may be fatal in a patient with dermatomyositis, we emphasize that a two dimensional echocardiographic study should be performed in all patient presenting with dermatopolymyositis.
AuthorsS Chraibi, H Ibnabdeljalil, R Habbal, A Bennis, A Tahiri, N Chraibi
JournalAnnales de medecine interne (Ann Med Interne (Paris)) Vol. 149 Issue 7 Pg. 464-6 (Nov 1998) ISSN: 0003-410X [Print] France
PMID9921402 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Inflammatory Agents
  • Antibodies, Antinuclear
  • Steroids
  • Rheumatoid Factor
Topics
  • Acute Disease
  • Adult
  • Anti-Inflammatory Agents (therapeutic use)
  • Antibodies, Antinuclear (analysis)
  • Biopsy
  • Cardiac Tamponade (diagnostic imaging, etiology, therapy)
  • Combined Modality Therapy
  • Dermatomyositis (complications, immunology)
  • Exudates and Transudates (chemistry)
  • Humans
  • Male
  • Pericardial Effusion (diagnostic imaging, etiology, therapy)
  • Pericardial Window Techniques
  • Rheumatoid Factor (analysis)
  • Steroids
  • Ultrasonography

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