Abstract | OBJECTS: Many studies show that sulfites cause multiple atopic manifestations by oral challenge in USA and Europe, however, there are few reports of sulfites sensitivity in Japan. The aim of this study establishes the presence of sulfites hypersensitivities in asthmatic subjects in Japan. SUBJECTS AND METHOD: Twenty adult asthmatic patients, who were non- steroid-dependent and without a suggestive history of sulfite sensitivity, underwent challenge with oral solution of metabisulfite. RESULT: CONCLUSION: Oral sulfite challenge should be made in patients with urticaria, that are not able to find out causative antigen, even though no suggestive history of sulfite sensitivity.
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Authors | Y Arai, H Muto, Y Sano, K Ito |
Journal | Arerugi = [Allergy]
(Arerugi)
Vol. 47
Issue 11
Pg. 1163-7
(Nov 1998)
ISSN: 0021-4884 [Print] Japan |
PMID | 9893332
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Food Preservatives
- Sulfites
|
Topics |
- Adult
- Asthma
(immunology)
- Female
- Food Hypersensitivity
(diagnosis, etiology)
- Food Preservatives
(adverse effects)
- Humans
- Male
- Middle Aged
- Sulfites
(adverse effects)
- Urticaria
(immunology)
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