HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Successful treatment of pustulosis palmaris et plantaris with granulocyte colony stimulating factor in a patient with hereditary neutropenia.

Abstract
A 26-year-old female with hereditary neutropenia had Pustulosis Palmaris et Plantaris. Drug administration did not improve her symptoms. Following administration of granulocyte colony stimulating factor (G-CSF; filgrastim), her neutrophil count increased from 300 to 58,000/microliters, and her dermatosis improved. Pustulosis Palmaris et Plantaris has been described as a representative second lesion of focal infection. Neutropenia may be one cause of Pustulosis Palmaris et Plantaris due to refractory focal infection. In the present case, increase in neutrophils with G-CSF may have improved focal infection, resulting in improvement in refractory Pustulosis Palmaris et Plantaris.
AuthorsM Hino, T Yamane, T Kuwaki, T Kono, S Kitagawa, N Tatsumi
JournalInternational journal of hematology (Int J Hematol) Vol. 68 Issue 4 Pg. 453-6 (Dec 1998) ISSN: 0925-5710 [Print] Japan
PMID9885446 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Granulocyte Colony-Stimulating Factor
Topics
  • Adult
  • Family Health
  • Female
  • Granulocyte Colony-Stimulating Factor (therapeutic use)
  • Humans
  • Neutropenia (complications, genetics)
  • Psoriasis (drug therapy, etiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: