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Dexamethasone-induced hepatomegaly in three children.

Abstract
High-dose treatment with dexamethasone led to reversible hepatomegaly with disturbance of liver function in three children. After withdrawal of dexamethasone, liver size and function returned to normal. These observations were compared with previously published data. The authors conclude that if this condition occurs, dexamethasone should be discontinued.
AuthorsA Verrips, J J Rotteveel, R Lippens
JournalPediatric neurology (Pediatr Neurol) Vol. 19 Issue 5 Pg. 388-91 (Nov 1998) ISSN: 0887-8994 [Print] United States
PMID9880147 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Dexamethasone
Topics
  • Child
  • Child, Preschool
  • Dexamethasone (adverse effects)
  • Female
  • Hepatomegaly (chemically induced, drug therapy)
  • Humans
  • Infant
  • Male
  • Splenomegaly (chemically induced, drug therapy)
  • Treatment Outcome

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