Abstract |
Silver coating of medical devices is believed to prevent device-associated infection. Several in-vitro and in-vivo studies, as well as clinical observations on silver- nylon, silver-intramedullary pins, silver oxide Foley catheters and silver-coated vascular prostheses have been performed during the past 30 years. Nevertheless, randomized clinical studies showing efficacy of such coated medical devices in high-risk patient populations are rare, have dealt with very small numbers of patients or are controversial. Physico-chemical, pharmacological and microbiological data explaining the antimicrobial efficacy of silver in prophylaxis of implants are presented here, as well as the scientific background for the established clinical benefits of silver-preparations in burns.
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Authors | J M Schierholz, L J Lucas, A Rump, G Pulverer |
Journal | The Journal of hospital infection
(J Hosp Infect)
Vol. 40
Issue 4
Pg. 257-62
(Dec 1998)
ISSN: 0195-6701 [Print] England |
PMID | 9868616
(Publication Type: Journal Article, Review)
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Chemical References |
- Coated Materials, Biocompatible
- Silver
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Topics |
- Blood Vessel Prosthesis
(adverse effects)
- Bone Nails
(adverse effects)
- Catheters, Indwelling
(adverse effects)
- Coated Materials, Biocompatible
(chemistry)
- Equipment Contamination
(prevention & control)
- Humans
- Materials Testing
- Prosthesis-Related Infections
(etiology, prevention & control)
- Silver
(chemistry)
- Urinary Catheterization
(instrumentation)
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