Effect of protein malnutrition on sex organs of metanil yellow exposed male rats.

Abstract

Oral administration of metanil yellow (MY) at 3.0% (w/w) dose level to adult male albino rats maintained on low protein (LP) diet for 30 days resulted in a greater decrease in absolute and relative weights of testes than in those rats maintained on a normal protein (NP) diet. A marked decrease in the activities of lactate dehydrogenase and hyaluronidase and content of lactic acid in LP + MY fed animals suggested that low protein diet enhanced the vulnerability of germ cells towards metanil yellow. The lack of significant changes in the cholesterol content of testis, the fructose content of the coagulating glands and the dorso-lateral prostate, the activities of alkaline phosphatase in the seminal vesicle, and acid phosphatase in ventral prostate of the MY treated animals suggested that their androgenic status were not affected.

• Authors: R L Singh
• Journal: Biomedical and environmental sciences : BES (Biomed Environ Sci) Vol. 11 Issue 3 Pg. 233-42 (Sep 1998) ISSN: 0895-3988 [Print] China
• PMID: 9861482 (Publication Type: Journal Article)

Chemical References

• Azo Compounds
• Food Coloring Agents
• Fructose
• metanil yellow
• Cholesterol
• Alkaline Phosphatase
• Acid Phosphatase

Topics

• Acid Phosphatase (drug effects, metabolism)
• Alkaline Phosphatase (drug effects, metabolism)
• Animals
• Azo Compounds (toxicity)
• Cholesterol (analysis)
• Food Coloring Agents (toxicity)
• Fructose (analysis)
• Male
• Nutrition Disorders
• Protein Deficiency (physiopathology)
• Rats
• Testis (drug effects, enzymology, pathology)