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[Writer's cramp treated with botulinum injections].

AbstractOBJECTIVE:
To evaluate the first clinical experience with local botulinum toxin A (BTA) injections in patients with writer's cramp.
DESIGN:
Descriptive.
SETTING:
Academic Medical Centre, Amsterdam, the Netherlands.
METHOD:
In May 1993-January 1996 ten patients with writer's cramp were treated with BTA (Dysport). Age of the patients varied from 28 to 68 years, the duration of complaints from 1 to 29 years. Muscles for injections were selected by observation, sometimes combined with electromyography. BTA was administered under electromyographic guidance.
RESULTS:
The amount of BTA administered per treatment session ranged from 15 to 400 IU. In three patients the BTA-induced weakness necessary to reach a beneficial effect on writing was unacceptable. In seven patients the response was satisfactory or good and lasted 2 to 15 months (mean: 3.5 months).
CONCLUSION:
The results confirm the efficacy of BTA in writer's cramp.
AuthorsJ H Koelman, M A Struys, B W Ongerboer de Visser, J D Speelman
JournalNederlands tijdschrift voor geneeskunde (Ned Tijdschr Geneeskd) Vol. 142 Issue 31 Pg. 1768-71 (Aug 01 1998) ISSN: 0028-2162 [Print] Netherlands
Vernacular TitleSchrijfkramp behandeld met botuline-injecties.
PMID9856142 (Publication Type: Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Neuromuscular Agents
  • Botulinum Toxins, Type A
Topics
  • Adult
  • Aged
  • Botulinum Toxins, Type A (adverse effects, therapeutic use)
  • Electromyography (methods)
  • Female
  • Hand
  • Handwriting
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Muscle Cramp (drug therapy)
  • Muscle Weakness (chemically induced)
  • Neuromuscular Agents (adverse effects, therapeutic use)
  • Treatment Outcome

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