[Clinical efficacy and safety of levocarbastine++ in the therapy in children suffering from seasonal allergic rhinitis and conjunctivitis who are less than 12 year of age].

Abstract

Levocabastine is an antihistaminic agent for topical application. It is without not advisable general side-effects and since many years is widely used for the treatment of pollinosis in adults and children more than 12 years of age. The group of 32 children aged from 5 to 11 years suffering from seasonal allergic rhinitis and conjunctivitis were treated by means of levocabastine applied topically by 20 days during the period of natural exposition to grass pollen. The clinical efficacy and tolerability including potential side-effects, were evaluated on the basis of clinical-laryngological investigations, visual analogs scales and diary cards filed in by parents of examined children. Levocabastine has been demonstrated to have rapid onset of action in children with SAR and the topical application of the drug does not irritate the mucosa of conjunctivas and nasal cavities.

• Authors: R Kurzawa, M Kossek, Z Doniec, H Mazurek, E Urbanek, I Sak-Kopytyńska, J Radliński, Z Bukowczan
• Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego (Pol Merkur Lekarski) Vol. 4 Issue 23 Pg. 269-72 (May 1998) ISSN: 1426-9686 [Print] Poland
• Vernacular Title: Ocena skuteczności klinicznej i bezpieczeństwa lewokabastyny w leczeniu pyłkowicy u dzieci ponizej 12. roku zycia.
• PMID: 9825660 (Publication Type: Clinical Trial, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Histamine H1 Antagonists
• Piperidines
• levocabastine

Topics

• Child
• Child, Preschool
• Conjunctivitis, Allergic (drug therapy)
• Histamine H1 Antagonists (therapeutic use)
• Humans
• Piperidines (therapeutic use)
• Rhinitis, Allergic, Seasonal (drug therapy)