Effect of intraocular acetylcholine and carbachol on the corneal endothelium. In vivo comparative study.

Abstract	The purpose of this study is to evaluate differences in corneal endothelial cell loss after intraocular use of two different miotics in subjects who have undergone extracapsular cataract extraction with posterior chamber intraocular lens implantation. The patients were divided into two groups: the first received 1 ml of 1% acetylcholine chloride and the second 0.5 ml of 0.01% carbachol as intraocular miotics. The endothelial count was done preoperatively and then 1 month after cataract extraction. There were no statistically significant differences in the mean cell loss between both groups. The authors believe that both miotics could be used in cataract surgery.
Authors	A M Roszkowska, G Ferreri, C A Squeri, P D'Angelo, F M Ferreri
Journal	Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde (Ophthalmologica) Vol. 212 Issue 6 Pg. 407-9 ( 1998) ISSN: 0030-3755 [Print] Switzerland
PMID	9787232 (Publication Type: Comparative Study, Journal Article)
Chemical References	Miotics Ophthalmic Solutions Carbachol Acetylcholine
Topics	Acetylcholine (administration & dosage, therapeutic use) Aged Carbachol (administration & dosage, therapeutic use) Cataract Extraction Cell Count Endothelium, Corneal (drug effects, pathology) Female Humans Male Middle Aged Miotics (administration & dosage, therapeutic use) Ophthalmic Solutions Postoperative Care Postoperative Period

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