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Autoimmune progesterone dermatitis: treatment with oophorectomy.

Abstract
Autoimmune progesterone dermatitis is a rare manifestation of hypersensitivity to endogenous hormones with polymorphic clinical manifestations. We report a 28-year-old woman with a 5-year history of mucocutaneous erythema multiforme occurring cyclically in the premenstrual period. Progesterone sensitivity was demonstrated by challenge test with medroxyprogesterone acetate. Treatments with oestrogens, tamoxifen and triptorelin had to be withdrawn because of intolerable adverse effects. Oophorectomy finally cured the disease.
AuthorsJ M Ródenas, M T Herranz, J Tercedor
JournalThe British journal of dermatology (Br J Dermatol) Vol. 139 Issue 3 Pg. 508-11 (Sep 1998) ISSN: 0007-0963 [Print] England
PMID9767301 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Progesterone
Topics
  • Adult
  • Autoimmune Diseases (pathology, surgery)
  • Erythema Multiforme (pathology, surgery)
  • Female
  • Humans
  • Ovariectomy
  • Progesterone (immunology)

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